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Updated: Jun 10, 2025
11:18
Direct Drug Delivery to Kidney via the Renal Artery
Published on: April 17, 2021
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Nanocarrier-Based Drug Delivery Systems Targeting Kidney Diseases
Laura Zucaro1,2, Consiglia Longobardi1,2, Antonio Miele1,2
1Biogem, Molecular Biology and Genetics Research Institute, Ariano Irpino, Italy.
Kidney & Blood Pressure Research
|October 15, 2024
Summary
Nanotechnology offers advanced nanocarriers for targeted drug delivery, imaging, and diagnostics in medicine. Optimizing nanocarrier properties can improve kidney access for treating various kidney diseases.
Area of Science:
- Nanomedicine
- Biotechnology
- Materials Science
Background:
- Nanotechnology's role in medicine is rapidly expanding, with nanocarriers showing promise.
- Nanocarriers are versatile tools for targeted drug delivery, medical imaging, and diagnostics.
- Advances in nanotechnology provide innovative solutions for complex health challenges.
Purpose of the Study:
- To review nanoparticle characteristics for enhanced kidney delivery.
- To explore how to overcome kidney structural barriers for nanocarrier passage.
- To discuss the potential of nanoparticles in treating kidney disorders.
Main Methods:
- Review of different nanoparticle types and their properties.
- Analysis of factors influencing kidney access, including size, shape, charge, and surface modification.
- Exploration of strategies for targeted delivery in the renal system.
Main Results:
- Nanoparticle characteristics can be tailored to improve kidney access.
- Optimization of nanocarriers can overcome biological barriers for targeted delivery.
- Nanotechnology holds potential for novel kidney disease therapies.
Conclusions:
- Nanotechnology offers significant advancements for improving therapeutic outcomes in kidney diseases.
- Tailoring nanocarrier properties is key to achieving effective renal targeting.
- Further research aims to develop targeted nanoparticle-based therapies for kidney disorders.
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