Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

11.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.5K
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

759
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
759
Viral Recombination00:57

Viral Recombination

23.3K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.3K
Stages of Infection01:26

Stages of Infection

55.7K
Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
55.7K
Infection01:20

Infection

7.7K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.7K
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

5.0K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
5.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[The path to wellness: a journey of body and spirit].

Zhonghua xin xue guan bing za zhi·2026
Same author

[Clinical features and genetic analysis for <i>PAX6</i>-associated ocular diseases].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same author

[From CKM to MCK: clinical implications of renaming cardiovascular-kidney-metabolic syndrome as metabolic-cardiovascular-kidney syndrome].

Zhonghua xin xue guan bing za zhi·2026
Same author

[Progress of mechanisms and treatment for mental stress-induced myocardial ischemia from a sex difference perspective].

Zhonghua nei ke za zhi·2026
Same author

[Causes and management strategies for unplanned reoperation after endoscopic middle ear surgery].

Zhonghua yi xue za zhi·2026
Same author

[Research advances on perirenal adipose tissue and chronic kidney injury in patients with cardiovascular disease].

Zhonghua xin xue guan bing za zhi·2025

Related Experiment Video

Updated: Jun 10, 2025

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

10.0K

[Can virus infection induce sepsis?]

J Z Weng1, Y M Li1

  • 1Department of Respiratory and Critical Care Medicine, Beijing Hospital, National Center of Gerontology,Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China.

Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases
|October 15, 2024
PubMed
Summary
This summary is machine-generated.

Sepsis, a life-threatening response to infection, requires effective pathogen detection and immune balancing. Research focuses on targeted treatments and personalized immunotherapies for better sepsis management.

More Related Videos

A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

148
A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
05:56

A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats

Published on: February 20, 2021

2.0K

Related Experiment Videos

Last Updated: Jun 10, 2025

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

10.0K
A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

148
A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
05:56

A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats

Published on: February 20, 2021

2.0K

Area of Science:

  • Infectious Diseases
  • Immunology
  • Critical Care Medicine

Background:

  • Sepsis is a critical condition arising from a dysregulated host response to infection, potentially leading to organ failure and death.
  • Severe viral infections can trigger sepsis, sharing physiological mechanisms with bacterial sepsis but requiring nuanced management.
  • Addressing sepsis necessitates antimicrobial treatment and restoring immune balance to interrupt the disease cycle.

Purpose of the Study:

  • To highlight the need for improved pathogen detection methods in sepsis.
  • To emphasize the importance of developing targeted antimicrobial agents.
  • To explore strategies for assessing host immune status and implementing individualized immunotherapies.

Main Methods:

  • Review of current understanding of sepsis pathophysiology.
  • Analysis of treatment strategies for bacterial and viral sepsis.
  • Discussion of diagnostic and therapeutic research directions.

Main Results:

  • Sepsis management hinges on effective antimicrobial therapy and immune homeostasis restoration.
  • Current approaches require enhancement in pathogen identification and targeted drug development.
  • Individualized immunotherapy based on dynamic immune status is a promising avenue.

Conclusions:

  • Accurate and rapid pathogen detection is crucial for timely sepsis intervention.
  • Targeted antimicrobial research is essential for combating diverse infectious agents.
  • Personalized immunotherapies hold potential for optimizing sepsis patient outcomes.