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Unveiling Sex Differences in Pediatric Burns Through the World Health Organization (WHO) Global Burn Registry

Joshua E Lewis1, Manav M Patel1, Shawn E Lim1

  • 1John Sealy School of Medicine, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-1317, USA.

Journal of Pediatric Surgery
|October 15, 2024
PubMed

Insights

Pediatric burn survivors, especially girls in low- and middle-income countries, face sex-based disparities in surgical care and are more likely to be discharged with disabilities. Addressing these differences is crucial for improving global burn outcomes.

Area of Science:

  • Global Health
  • Pediatric Surgery
  • Burn Medicine

Background:

  • Pediatric burns represent a substantial global health issue, disproportionately affecting low- and middle-income countries (LMICs).
  • Limited research has investigated sex-based disparities in pediatric burn incidence and outcomes worldwide.
  • This study addresses the gap by examining sex differences in pediatric burns, comparing LMICs and high-income countries (HICs).

Purpose of the Study:

  • To analyze global sex-based differences in pediatric burn incidence.
  • To assess variations in burn care facility capacities concerning sex.
  • To compare pediatric burn outcomes between sexes in LMICs and HICs.

Main Methods:

  • Retrospective observational study utilizing the World Health Organization's (WHO) Global Burn Registry (GBR) from 2018 to 2022.
  • Analysis included pediatric burn cases, demographics, burn causes, facility capacities, and outcomes, stratified by sex.
  • Statistical methods included chi-square and logistic regression analyses.

Main Results:

  • Female pediatric burn patients in LMICs were less likely to receive surgical treatment compared to males.
  • Females in both low- and middle-income countries had significantly higher odds of discharge with a disability than males.
  • Adjusted odds ratios indicated statistically significant differences in surgical treatment and disability outcomes based on sex in LMICs.

Conclusions:

  • Persistent sex-based disparities exist in pediatric burn epidemiology and treatment outcomes.
  • Implementing sex-sensitive strategies is essential to reduce the global burden of pediatric burns.
  • Vulnerable populations, particularly in LMICs, require targeted interventions to address these sex-based inequities.
Abstract

Keywords:
BurnsGlobal burn registryPediatric burnsSex differencesWorld health organization

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