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A Comprehensive Review on Deep Eutectic Solvents: Their Current Status and Potential for Extracting Active Compounds
Malgorzata Stanisz1, Beata J Stanisz2, Judyta Cielecka-Piontek3
1Department of Pharmacology and Phytochemistry, Institute of Natural Fibres and Medicinal Plants, Kolejowa 2, PL, 62-064 Poznan, Poland.
Molecules (Basel, Switzerland)
|October 16, 2024
Summary
Deep eutectic solvents (DESs) offer an eco-friendly alternative for extracting adaptogenic compounds from medicinal herbs. These novel solvents provide a greener approach compared to traditional methods, reducing reliance on harmful organic solvents.
Area of Science:
- Green Chemistry
- Phytochemistry
- Solvent Engineering
Background:
- Adaptogenic herbs possess bioactive compounds with significant pharmaceutical properties.
- Traditional extraction methods often rely on hazardous organic solvents and harsh conditions.
- Deep eutectic solvents (DESs) are emerging as tunable, low-toxicity alternatives.
Purpose of the Study:
- To review the application of deep eutectic solvents (DESs) for extracting adaptogenic compounds.
- To highlight DESs as a sustainable alternative to conventional extraction techniques.
- To discuss the properties and applications of compounds extracted using DESs.
Main Methods:
- Literature review focusing on DESs for adaptogen extraction.
- Analysis of DES properties, including polarity and tunability.
- Evaluation of extraction efficiency and comparison with traditional methods.
Main Results:
- DESs demonstrate significant potential for extracting various active compounds (saponins, flavonoids, etc.).
- Extraction using DESs can be performed under mild conditions, enhancing compound stability.
- DESs offer a versatile and environmentally friendly alternative to organic solvents.
Conclusions:
- Deep eutectic solvents represent a promising green technology for the sustainable extraction of valuable compounds from adaptogenic herbs.
- Further research into DES applications can optimize extraction processes and expand their use in the pharmaceutical industry.

