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Functional Characterization of Carboxylesterases in Insecticide Resistant House Flies, Musca Domestica
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Unveiling the Role of Two Rhodopsin-like GPCR Genes in Insecticide-Resistant House Flies, Musca domestica

Juanjuan Xin1, Dylan Brown1, Yifan Wang1

  • 1Department of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849, USA.

International Journal of Molecular Sciences
|October 16, 2024
PubMed
Summary

Two G-protein-coupled receptor (GPCR) genes were identified as key regulators of insecticide resistance in house flies. Overexpression of these genes enhanced insecticide detoxification by upregulating P450 enzymes, offering new targets for resistance management.

Keywords:
G-protein coupled receptors (GPCRs)cytochrome P450sgene mappinghouse fliesinsecticide resistance

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