The Cancer Patient Empowerment Program: A Comprehensive Approach to Reducing Psychological Distress in Cancer...

Area of Science:

• Oncology
• Psychology
• Health Intervention Studies

Background:

• Psychological distress is a significant concern for cancer patients, impacting quality of life and treatment adherence.
• The Cancer Patient Empowerment Program (CancerPEP) is a home-based intervention combining physical activity, dietary guidance, and social support.
• This study evaluated CancerPEP's feasibility, safety, and effectiveness in reducing psychological distress.

Purpose of the Study:

• To assess the effectiveness of the CancerPEP intervention, with and without a Heart Rate Variability (HRV) biofeedback device, on psychological distress.
• To evaluate feasibility, accrual, attrition rates, and safety of the CancerPEP intervention.
• To analyze the impact of group randomization and pre- vs. post-intervention differences on psychological distress.

Main Methods:

• A single-site, crossover randomized clinical trial involving 104 cancer patients.
• Participants received CancerPEP with or without an HRV biofeedback monitor.
• Psychological distress was measured using the Kessler Psychological Distress Scale (K10) at baseline, 6 months, and 12 months.

Main Results:

• CancerPEP significantly reduced psychological distress over time (aOR = 2.64, 95% CI: 1.53-4.56).
• The HRV biofeedback monitor did not significantly affect the primary outcome.
• No adverse events were observed; approximately 10% of participants were lost to follow-up.

Conclusions:

• CancerPEP effectively reduces psychological distress in cancer patients across various types and stages.
• The intervention shows promise for survivorship care and can be tailored to specific patient needs.
• Further research, including trials with usual care control groups, is needed to integrate CancerPEP into standard oncology care.