Evaluation of Peri-Operative Outcomes after Prostatic Urethral Lift with Emphasis on Urodynamic Changes, Symptom...

Area of Science:

• Urology
• Medical Devices
• Surgical Innovation

Background:

• Benign prostatic hyperplasia (BPH) causes lower urinary tract symptoms (LUTS).
• Prostatic urethral lift (PUL) is a minimally invasive treatment option for BPH.
• Urodynamic evaluation is crucial for assessing treatment efficacy in BPH.

Purpose of the Study:

• To evaluate the urodynamic effects of Prostatic Urethral Lift (PUL).
• To assess PUL's impact on lower urinary tract symptoms (LUTS) and bladder outlet obstruction in benign prostatic hyperplasia (BPH) patients.
• To determine if PUL affects sexual function.

Main Methods:

• Prospective enrollment of 20 BPH patients (age ≥50) across two centers.
• Baseline and 6-month assessments included clinical history, IPSS, cystoscopy, and pressure flow studies (PFS).
• Inclusion criteria: BPH, IPSS ≥13, prostate volume ≤60 mL, no middle lobe.

Main Results:

• Significant improvements observed in median Qmax (11.5 vs. 8.5, p<0.05) and median IPSS (16 vs. 10.5, p<0.05) at 6 months.
• Urodynamic parameters improved, with notable enhancement in Schäfer's class (median III to II).
• Sexual function was maintained, and 12/20 patients achieved BOOI < 20, indicating reduced obstruction.

Conclusions:

• Prostatic urethral lift (PUL) is an effective treatment for LUTS in BPH.
• PUL successfully improves bladder outlet obstruction.
• PUL does not adversely affect sexual function in treated patients.