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Equilibrium Optimization-Based Ensemble CNN Framework for Breast Cancer Multiclass Classification Using

Yasemin Çetin-Kaya1

  • 1Department of Computer Engineering, Faculty of Engineering and Architecture, Tokat Gaziosmanpasa University, Tokat 60250, Turkey.

Diagnostics (Basel, Switzerland)
|October 16, 2024
PubMed
Summary

A novel deep learning model, MultiHisNet, accurately diagnoses eight types of breast cancer from histopathological images, aiding early detection and improving patient outcomes.

Keywords:
breast cancer classificationdeep learningensemble learningequilibrium optimizerhistopathological image

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Area of Science:

  • Oncology
  • Medical Imaging
  • Artificial Intelligence

Background:

  • Breast cancer remains a leading cause of mortality in women.
  • Early detection and accurate diagnosis are crucial for effective treatment and reduced mortality.
  • Histopathological images are vital for breast cancer diagnosis and staging.

Purpose of the Study:

  • To develop a high-performance deep learning model for diagnosing eight types of breast cancer.
  • To address challenges in histopathological image analysis, including data imbalance and model overfitting.
  • To propose a novel model, MultiHisNet, for improved breast cancer classification.

Main Methods:

  • Utilized the BreakHis dataset of histopathological images.
  • Fine-tuned 20 state-of-the-art deep learning models.
  • Developed and evaluated 20 custom models, including the novel MultiHisNet.
  • Created an ensemble model using best-performing models and an Equilibrium Optimizer.

Main Results:

  • The novel MultiHisNet model achieved 94.69% accuracy in multi-class breast cancer classification.
  • The proposed ensemble model reached 96.71% accuracy in eight-class breast cancer detection.
  • The study identified key components for effective model performance, such as attention modules and residual links.

Conclusions:

  • The developed deep learning models, particularly the ensemble approach, demonstrate high accuracy in breast cancer diagnosis.
  • The findings suggest that the proposed model can serve as a valuable tool to assist pathologists.
  • This research contributes to advancing automated breast cancer diagnosis through artificial intelligence.