Sex and Population Variations in Nasopalatine Canal Dimensions: A CBCT-Based Systematic Review

The nasopalatine canal (NPC), an interosseous conduit in the anterior maxilla, plays a crucial role in various dental procedures, such as implant placement, orthodontics, and surgical interventions. Accurate anatomical characterization of the NPC is essential to avoid complications, as its morphometric variations can impact the nasopalatine nerve and vascular structures within the canal. Traditional radiography techniques are limited in displaying the canal's detailed anatomy due to issues like magnification and distortion. Cone beam computed tomography (CBCT), with its superior imaging quality and reduced radiation exposure, has become the preferred method for NPC evaluation. This systematic review aimed to evaluate the published literature on the variations in anatomy and dimensions of the NPC using CBCT. A complete literature search was conducted in Web of Science, PubMed/Medline, EMBASE, Scopus, Cochrane Library, Google Scholar, and ProQuest electronic databases. The following keywords were used alone or combined: CBCT, measurements [(nasopalatine canal length), (incisive foramen), (foramina of Stenson), (buccal bone plate), gender, plane as (oblique measurements), or (sagittal or axial). Papers were manually searched utilizing their reference titles. Research selection was restricted to the time of publication but not to the type of tested publication from different countries or sex and NPC parameter measurements. Fourteen full-length papers were included. Parameters like NPC length and diameters of incisive foramen (IF) and foramina of Stenson (FS) were generally higher in males than females, with significant differences noted across most studies. NPC dimensions are influenced by sex, with males typically exhibiting larger measurements. Additionally, NPC dimensions vary among different populations.