Effect of ozonated oil versus chlorhexidine gel among Indian patients with chronic periodontitis

The efficacy of Ozonated oil in treating chronic periodontitis compared to Chlorhexidine gel following Scaling and Root Planing (SRP) is of interest. Fifty-six patients were randomly assigned to two groups: one receiving Ozonated oil post-SRP and the other receiving Chlorhexidine gel. Periodontal indices (Plaque Index, Gingival Index), Periodontal Probing Depth (PPD), and Clinical Attachment Level (CAL) were measured at baseline, one month, and three months. Intragroup comparisons for Plaque and Gingival indices showed statistically significant improvements over time (p < 0.05), but intergroup comparisons did not reveal significant differences. However, both groups demonstrated statistically significant improvements in PPD and CAL at all-time points (p < 0.05). Further research is warranted to explore Ozonated oil's potential as an antimicrobial treatment for chronic periodontitis and other oral microbial infections.