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Setup of Capillary Electrophoresis-Inductively Coupled Plasma Mass Spectrometry (CE-ICP-MS) for Quantification of Iron Redox Species (Fe(II), Fe(III))
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Chloroquine reduces neuronal and glial iron uptake

K F Swaiman, V L Machen

    Journal of Neurochemistry
    |February 1, 1986
    PubMed

    Abstract:

    The effect of chloroquine, a lysosomotropic agent, on iron uptake into neuronal and glial cell cultures is reported. Chloroquine significantly inhibited iron uptake in both neuronal and glial cells. These findings suggest that iron transport into both neuronal and glial cells is mediated by the transferrin-iron complex.

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