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Updated: Jun 10, 2025
Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
Published on: October 6, 2023
Thyroid Disease of Fishes
Peter M DiGeronimo1, E Scott P Weber2
1Philadelphia Zoo, 3400 West Girard Avenue, Philadelphia, PA 19104, USA.
Abstract:
The paraphyletic group referred to as fishes represents several extant and extinct classes that demonstrate the greatest diversity and abundance of any of the vertebrates on the Earth. Anatomically and physiologically, the systems of fish are comparable to those of other vertebrates and the thyroid and hypothalamic-pituitary-thyroid (HPT) axis are no exceptions. This article reviews the current literature on thyroid endocrinology of elasmobranch and teleost fishes with an emphasis on relevance to clinical management and highlights some of the anatomic and physiologic differences of the HPT axis in fishes.
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