Reply to: "Long-term survival analysis of free flap reconstruction in patients with collagen vascular disorders"

Related Experiment Video

Updated: Jul 2, 2026

Engineered Vascularized Muscle Flap
08:18

Engineered Vascularized Muscle Flap

Published on: January 11, 2016

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Emma Barlow1, Zita M Jessop2, Giulia Colavitti1

  • 1Department of Plastic Surgery, North Bristol NHS Foundation Trust, Southmead Hospital, Southmead Rd, Bristol BS10 5NB, United Kingdom.

Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS
|October 16, 2024
PubMed
Abstract

No abstract available in PubMed .

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Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...