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Updated: Jun 10, 2025
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Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection
Published on: February 9, 2024
899
Target-assisted self-cleavage DNAzyme electrochemical biosensor for MicroRNA detection with signal amplification
Juan Zhang1, Benting Xie1, Haonan He1
1College of Chemistry and Chemical Engineering, Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, Institute of Applied Chemistry, China West Normal University, Nanchong, Sichuan 637000, China. liaofang407@163.com.
Chemical Communications (Cambridge, England)
|October 17, 2024
Abstract:
In this work, we reported an electrochemical biosensor with target-assisted self-cleavage DNAzyme function for signal amplified detection of miRNA. The target-recycling amplification led to significant signal enhancement and thus offers high detection sensitivity.
