Related Experiment Video
Updated: Jun 10, 2025
Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
Published on: January 20, 2022
Novel method for assessing sinusoidal obstruction syndrome using four-dimensional computed tomography
Saori Shimoyama-Ibuki1, Satoshi Iyama1,2, Yoshiya Ohashi3
1Department of Hematology Sapporo Medical University School of Medicine Sapporo Japan.
Introduction:
To diagnose sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD), transabdominal ultrasonography is usually used to detect hemodynamic changes, but we tried to detect the changes using four-dimensional computed tomography (4D-CT). A 42-year-old Japanese woman was diagnosed with late-onset SOS/VOD with transabdominal ultrasonography and was also assessed using 4D-CT. Method We analyzed the portal vein (PV) contrast effect every 1.5 seconds and plotted the values of the contrast effect. With this graph, we analyzed three hemodynamic parameters.
Result:
We found that these parameters correlated with the patient's status and indicated stasis due to sinusoid constriction.
Conclusion:
4D-CT may become a helpful tool to diagnose and follow up with SOS/VOD.
