Ureter-ileum-interposition: Combined experience from two high-volume centres

Area of Science:

• Urology
• Surgical Oncology
• Nephrology

Background:

• Ileal ureter interposition is a reconstructive surgical technique used in urology.
• Evaluating its safety and efficacy is crucial for patient outcomes.

Purpose of the Study:

• To assess short- and long-term complication rates.
• To evaluate functional outcomes after ileal ureter interposition.
• To analyze data from a substantial patient cohort at high-volume centers.

Main Methods:

• Retrospective single-arm analysis of 107 patients (2003-2022).
• Data collected on etiology, surgical techniques, kidney function (eGFR), readmissions, and complications (Clavien-Dindo classification).
• Kidney function assessed using CKD-EPI formula.

Main Results:

• 53% of patients experienced complications within 90 days (mostly Grade I-II).
• 15% developed anastomosis stricture; 28% had significant vesico-renal reflux.
• Improved renal function observed in 52% of patients post-surgery, with a 90-day mortality rate of 1.8%.

Conclusions:

• Ileal ureter interposition demonstrates a favorable safety profile.
• The procedure yields positive functional outcomes for patients.
• It serves as an effective tension-free ureteral bypass option.