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Prognostic Value of PRECİSE DAPT Score on Short- and Long-Term Outcomes in MINOCA Patients with Acute Coronary

Tolga Onuk1, Fuat Polat1, Bariş Yaylak1

  • 1Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Education Research Hospital, Istanbul - Turquia.

Arquivos Brasileiros De Cardiologia
|October 17, 2024
PubMed
Abstract

Insights

The PRECISE-DAPT score effectively predicts major adverse cardiovascular events (MACE) in patients with myocardial infarction with non-obstructive coronary arteries (MINOCA). Higher scores indicate increased risks for both in-hospital and long-term MACE.

Area of Science:

  • Cardiology
  • Clinical Medicine
  • Cardiovascular Research

Background:

  • Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a significant subset of acute myocardial infarctions (AMI) with unclear prognostic markers.
  • Early risk stratification is essential for identifying MINOCA patients at risk of adverse outcomes.

Purpose of the Study:

  • To evaluate the predictive capability of the PRECISE-DAPT score for short- and long-term prognoses in MINOCA patients.
  • To assess the score's association with major adverse cardiovascular events (MACE) in MINOCA patients presenting with ST-segment elevation myocardial infarction (STEMI) or non-ST-elevation myocardial infarction (NSTEMI).

Main Methods:

  • The PRECISE-DAPT score was calculated for 741 MINOCA patients.
  • Statistical analyses included univariate and multivariate logistic and Cox regressions to assess the association between the PRECISE-DAPT score and in-hospital/follow-up MACE.
  • Significance was determined using a predefined level of α = 0.05.

Main Results:

  • In-hospital MACE occurred in 4.1% of patients; 58% experienced follow-up MACE.
  • Hemoglobin levels and the PRECISE-DAPT score were independent predictors of in-hospital MACE.
  • Ejection fraction (EF%) and the PRECISE-DAPT score independently predicted follow-up MACE.

Conclusions:

  • A higher PRECISE-DAPT score is significantly linked to increased risks of in-hospital and long-term MACE in MINOCA patients.
  • The PRECISE-DAPT score shows potential for risk stratification in MINOCA patients presenting with acute coronary syndrome (ACS).
  • Hemoglobin and ejection fraction also play roles in predicting MACE in this cohort.

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