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Hyponatraemia complicating the treatment of myxoedema coma. A case report
Abstract:
Hyponatraemia is a common complication of severe hypothyroidism, but is usually readily corrected by administering L-thyroxine. A case of myxoedema coma in which the serum sodium level dropped precipitously when therapy was started is described and it is suggested that this was due to a state of relative hypocortisolism. Serum sodium values should be closely monitored in myxoedema treated with L-thyroxine; their decrease may signal the onset of an Addisonian-like crisis requiring urgent corticosteroid supplementation.
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