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Updated: Jun 10, 2025

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
Published on: August 2, 2017
The human claustrum tracks slow waves during sleep
Layton Lamsam1, Brett Gu1, Mingli Liang1
1Department of Neurosurgery, Yale School of Medicine, Yale University, New Haven, CT, USA.
Abstract:
Slow waves are a distinguishing feature of non-rapid-eye-movement (NREM) sleep, an evolutionarily conserved process critical for brain function. Non-human studies suggest that the claustrum, a small subcortical nucleus, coordinates slow waves. We show that, in contrast to neurons from other brain regions, claustrum neurons in the human brain increase their spiking activity and track slow waves during NREM sleep, suggesting that the claustrum plays a role in coordinating human sleep architecture.
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