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Updated: Jun 10, 2025

Isolation of Primary Murine Brain Microvascular Endothelial Cells
Published on: November 14, 2014
Pioneering discovery and therapeutics at the brain-vascular-immune interface
Katerina Akassoglou1, Dimitrios Davalos2, Andrew S Mendiola3
1Center for Neurovascular Brain Immunology at Gladstone and UCSF, San Francisco, CA 94158, USA; Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
None:
The brain-vascular-immune interface has emerged as a dynamic player in brain physiology and disease. We propose integrating vascular risk factors with genetic susceptibility as the nexus for the discovery of mechanisms and therapies for neuroinflammation, neurodegeneration, and neurorepair across polygenic neurologic diseases.
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