Related Experiment Video
Updated: Jun 10, 2025

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Post-surgical endophthalmitis with secondary meningitis. About a case
S Hernández Santamaría1, N García Figuera1, M Maldonado MacCrohon1
1Servicio de Oftalmología, Hospital Universitario de Getafe, Getafe, Madrid, Spain.
Abstract:
A 61-year-old man presented hyperacute endophthalmitis due to Proteus mirabilis after a pars plana vitrectomy. In the first examination (24 h after surgery), visual acuity (VA) was of hand movement, biomicroscopy showed edematous cornea, Tyndall ++++ and fibrin membrane, with vitritis and impossibility of visualizing retina details. Treatment with intravitreal injections was performed. Despite the treatment, the patient's symptoms worsened, and he began with poor general condition, fever, and leukocytosis, requiring hospitalization and intravenous treatment because of a diagnosis of secondary meningitis due to post-surgical endophthalmitis. The patient required enucleation of the affected eye without prosthesis placement. Even though post-surgical bacterial endophthalmitis is usually an infection confined to the eye, this clinical case demonstrates the possibility of the infection spreading to the rest of the body, potentially endangering the patient's life.
Related Concept Videos
Glaucoma: Overview
Acute Pyelonephritis II: Diagnostic Studies and Management
Endocarditis III: Medical Management

