Medicare Advantage Is Associated With Higher Mortality After Antibiotic Spacer Placement for Periprosthetic Joint

Nathanael D Heckmann1, Julian Wier1, Kevin C Liu1

  • 1Department of Orthopaedic Surgery, Keck Medical Center of the University of Southern California, Los Angeles, California.

PubMed
Abstract

Insights

Medicare Advantage (MA) patients undergoing hip or knee surgery for periprosthetic joint infection (PJI) had higher 90-day mortality compared to traditional Medicare (TM) patients. This study highlights potential disparities in outcomes for MA enrollees.

Area of Science:

  • Orthopedic Surgery
  • Health Services Research
  • Public Health

Background:

  • Medicare Advantage (MA) plans offer an alternative to traditional Medicare (TM).
  • Periprosthetic joint infection (PJI) is a serious complication following hip or knee replacement surgery.
  • Stage 1 antibiotic spacer placement is a critical intervention for managing PJI.

Purpose of the Study:

  • To compare 90-day postoperative mortality and adverse events between TM and MA patients undergoing stage 1 antibiotic spacer placement for PJI.
  • To identify potential disparities in surgical outcomes based on insurance type.

Main Methods:

  • A retrospective analysis of a national database (2015-2021) identified adult patients undergoing stage 1 antibiotic spacer placement for PJI.
  • Patients were stratified into TM and MA cohorts based on insurance coverage.
  • Multivariable logistic regression analyses were performed to adjust for demographic, comorbidity, and hospital-related confounders.

Main Results:

  • The study included 40,346 patients, with 16,637 (41.2%) in the TM cohort and 9,218 (22.8%) in the MA cohort.
  • Ninety-day postoperative mortality was higher in the MA cohort (1.4%) compared to the TM cohort (1.0%) (P = 0.004).
  • Adjusted analyses revealed significantly higher odds of mortality for MA patients (aOR = 1.42, 95% CI = 1.11-1.81, P = 0.005).

Conclusions:

  • Patients enrolled in Medicare Advantage plans demonstrated a >40% increased likelihood of 90-day mortality following stage 1 PJI surgery compared to traditional Medicare beneficiaries.
  • These findings persist even after controlling for known confounding factors.
  • Further research is warranted to elucidate the specific reasons behind this observed outcome disparity.

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