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Cefiderocol pharmacokinetics in critically ill patients undergoing ECMO support

María Marín-Cerezuela1, Ruben Martín-Latorre2, Juan Frasquet3

  • 1Pharmacy Department, Hospital Universitario y Politécnico la Fe, Valencia, Spain.

Critical Care (London, England)
|October 18, 2024
PubMed
Summary

No abstract available in PubMed .

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Renal Failure: Dose Adjustments01:11

Renal Failure: Dose Adjustments

In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
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