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Neutral oligosaccharides from ginseng (Panax ginseng) residues vs. neutral ginseng polysaccharides: A comparative
Li Tao1, Jingwei Zhang1, Wenfei Lan1
1College of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, China.
Abstract:
This study aimed to compare the structural and biological activities of neutral ginseng residue oligosaccharides (GRO-N) and neutral ginseng polysaccharides (GP-N). Their structures of GRO-N and GP-N were established based on their molecular weight (Mw), monosaccharide composition, Fourier-transform infrared spectroscopy, methylation, and nuclear magnetic resonance analyses. The Mws of GRO-N and GP-N were 1121.0 Da and 12,791.0 Da, respectively. Both had major chain structures comprising α-D-Glcp-(1→, →4)-α-D-Glcp-(1→, and →4)-α/β-D-Glcp, with branch points at →4,6)-α-D-Glcp-(1→. Moreover, the branched chain of GRO-N was α-D-Glcp-(1→ and →6)-α-D-Glcp-(1→. The branched chain of GP-N was α-D-Glcp-(1→ and →4)-α-D-Glcp-(1→. GRO-N, with a lower Mw and more diverse glycosidic bonds, exhibited higher antioxidant, hypoglycemic, and immune activities than GP-N. Cell viability peaked (202.81 ± 4.80 %) at a GRO-N concentration of 200 μg/mL. These findings provide a theoretical basis for further utilization of ginseng residual saccharides.
