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Related Experiment Videos

Candida vegetations on silicone voice prostheses.

H F Mahieu, H K van Saene, H J Rosingh

    Archives of Otolaryngology--Head & Neck Surgery
    |March 1, 1986
    PubMed
    Summary
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    Candida organisms in voice prostheses cause malfunctions. Preventing fungal growth on these devices may extend their lifespan for patients undergoing voice rehabilitation.

    Area of Science:

    • Biomedical Engineering
    • Microbiology
    • Otolaryngology

    Background:

    • Silicone voice prostheses are crucial for voice rehabilitation after laryngectomy.
    • Malfunctions in these devices are often attributed to surface deposits.
    • The composition and origin of these deposits require detailed investigation.

    Purpose of the Study:

    • To identify the microbial agents responsible for voice prosthesis malfunction.
    • To investigate the adherence and penetration of these agents into the silicone material.
    • To explore potential strategies for preventing prosthesis failure.

    Main Methods:

    • Culturing techniques to identify microorganisms.
    • Scanning electron microscopy (SEM) to visualize microbial colonization.

    Related Experiment Videos

  • Examination of explanted silicone voice prostheses.

    • Main Results:

    • Deposits were identified as Candida organisms.
    • Candida colonized both the surface and the bulk of the silicone material.
    • Patients showed no apparent adverse effects from the Candida colonization.

    Conclusions:

    • Candida overgrowth is a primary cause of voice prosthesis valve dysfunction.
    • Strategies like oropharyngeal decontamination or prosthesis coating may improve device longevity.
    • Further research into antifungal treatments and material modifications is warranted.