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[Lessons on reactions to aesthetic fillers]
1Cabinet Mathurin Moreau/Xpath, Paris, France; Service de pathologie de Cochin, hôpital Cochin, Paris, France.
Annales De Pathologie
|October 19, 2024
Summary
Injectable wrinkle fillers can cause granulomatous reactions, even years later. Hyaluronic acid is common, but immune disorders or COVID-19 vaccination can trigger reactions in older injections.
Area of Science:
- Dermatology
- Immunology
- Plastic Surgery
Context:
- Injectable dermal fillers are widely used for cosmetic wrinkle correction.
- Various filler materials exist, with hyaluronic acid being the most prevalent due to its resorbable nature.
- Foreign body reactions, including granulomas, are known complications of injectable substances.
Purpose:
- To discuss the potential for granulomatous reactions following cosmetic injections.
- To highlight factors that may predispose individuals to such reactions, particularly in the context of immune system modulation.
Summary:
- Injectable products used for wrinkle filling can elicit foreign body responses, manifesting as granulomas.
- Hyaluronic acid is a common filler, generally considered less toxic and resorbable.
- Granuloma formation can occur even with long-standing injections, especially in patients with underlying immune disorders like sarcoidosis or following vaccinations such as COVID-19.
Impact:
- Understanding these risks is crucial for clinicians performing aesthetic procedures.
- Patient selection and awareness of potential delayed reactions are important considerations.
- This information aids in managing and preventing adverse events associated with cosmetic fillers.
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