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Related Concept Videos

Pulse rhythm01:30

Pulse rhythm

768
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
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Related Experiment Video

Updated: Jun 10, 2025

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
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Chronic wireless communication between dual-chamber leadless pacemaker devices.

Rahul N Doshi1, James E Ip2, Pascal Defaye3

  • 1HonorHealth Cardiac Arrhythmia Group, Scottsdale, Arizona.

Heart Rhythm
|October 20, 2024
PubMed
Summary
This summary is machine-generated.

The Aveir DR leadless pacemaker system demonstrated over 90% implant-to-implant communication success. This wireless technology showed significant improvement over six months, enhancing pacing reliability.

Keywords:
AveirDual-chamberImplant-to-implant communicationLeadless pacemakeri2i

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Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Devices

Background:

  • The Aveir DR is a novel dual-chamber leadless pacemaker (LP) system.
  • It utilizes distinct wireless atrial and ventricular LPs (ALP, VLP) for atrioventricular synchronous pacing.
  • Chronic implant-to-implant (i2i) transmission success rates required systematic evaluation.

Purpose of the Study:

  • To evaluate the chronic success rates of wireless implant-to-implant (i2i) transmissions in a clinical setting.
  • To assess the reliability of communication between the atrial and ventricular leadless pacemakers.

Main Methods:

  • Prospective international clinical trial (Aveir DR i2i Study) involving 399 patients.
  • Interrogation of i2i transmission success rates (A-to-V and V-to-A) at implant, discharge, and 1, 3, and 6 months post-implant.
  • Analysis included patients with standard dual-chamber pacing indications.

Main Results:

  • Median i2i success rates exceeded 90% of beats throughout the 6-month follow-up.
  • Patients with initial low i2i success (<70%) showed significant improvement by 1 month.
  • By 6 months, only approximately 5% of patients experienced persistent low i2i success.

Conclusions:

  • The Aveir DR leadless pacemaker system achieves high (>90%) wireless i2i communication success.
  • Communication reliability improves over time, particularly in subgroups with initial challenges.
  • This demonstrates the clinical viability of leadless dual-chamber pacing technology.