Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Symbiosis

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Decoding the multifaceted role of erythrocyte PMCA4b in oxidative stress-mediated malaria protection and artemisinin resistance.

mBio·2025

Same author

Evolution of tandem repeats in putative circumsporozoite protein to enhance its function: A recent and exclusive event in <i>Plasmodium vivax</i> in India.

Current research in microbial sciences·2025

Same author

Clinical and parasitological efficacy of artesunate and sulfadoxine-pyrimethamine (AS+SP) for the treatment of uncomplicated falciparum malaria in different transmission settings in India.

Journal of vector borne diseases·2025

Same author

Distinct methylome profile of cfDNA in AMI patients reveals significant alteration in cAMP signaling pathway genes regulating cardiac muscle contraction.

Clinical epigenetics·2024

Same author

An update on the cell-free DNA-derived methylome as a non-invasive biomarker for coronary artery disease.

The international journal of biochemistry & cell biology·2024

Same author

Donor-Derived Cell-Free DNA as a Non-Invasive Biomarker for Graft Rejection in Kidney Transplant Recipients: A Prospective Study among the Indian Population.

Diagnostics (Basel, Switzerland)·2023

Search research articles

Related Experiment Video

Updated: Jun 10, 2025

A Multi-detection Assay for Malaria Transmitting Mosquitoes

A Multi-detection Assay for Malaria Transmitting Mosquitoes

Published on: February 28, 2015

Microhaplotypes: the QR-code for Plasmodium vivax infection dynamics.

Manoswini Dash¹, Prashant Kumar Mallick²

¹Centre for Aging, School of Medicine, Tulane University, New Orleans, LA, USA.

Trends in Parasitology

|October 20, 2024

Summary

Microhaplotypes, short DNA segments, can distinguish Plasmodium vivax relapse or reinfection events. Further validation is needed to confirm their widespread use in malaria-endemic regions.

Keywords:

Plasmodium vivax genetic complexity identity-by-descent lineage microhaplotype relapse

More Related Videos

Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria

Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria

Published on: November 10, 2015

Protocol for Plasmodium falciparum Infections in Mosquitoes and Infection Phenotype Determination

Protocol for Plasmodium falciparum Infections in Mosquitoes and Infection Phenotype Determination

Published on: July 4, 2007

Related Experiment Videos

Last Updated: Jun 10, 2025

A Multi-detection Assay for Malaria Transmitting Mosquitoes

A Multi-detection Assay for Malaria Transmitting Mosquitoes

Published on: February 28, 2015

Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria

Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria

Published on: November 10, 2015

Protocol for Plasmodium falciparum Infections in Mosquitoes and Infection Phenotype Determination

Protocol for Plasmodium falciparum Infections in Mosquitoes and Infection Phenotype Determination

Published on: July 4, 2007

Area of Science:

Genetics
Malariology
Genomic Epidemiology

Background:

Plasmodium vivax causes significant global malaria burden.
Distinguishing between relapse and new infections is crucial for effective malaria control.
Current methods for tracking malaria transmission and relatedness have limitations.

Purpose of the Study:

To introduce and evaluate the utility of Plasmodium vivax microhaplotypes.
To assess the potential of microhaplotypes for distinguishing P. vivax relapse/reinfection.
To explore the application of microhaplotypes in identifying genetic relatedness in P. vivax.

Main Methods:

Identification of microhaplotypes within the Plasmodium vivax genome.
Analysis of microhaplotype allelic combinations.
Assessment of microhaplotype discriminatory power for infection origins.

Main Results:

An array of microhaplotypes was identified in the Plasmodium vivax genome.
Microhaplotypes demonstrated potential in distinguishing P. vivax relapse from reinfection.
Microhaplotypes showed promise in assessing genetic relatedness across endemic areas.

Conclusions:

Plasmodium vivax microhaplotypes are a promising genetic tool.
Microhaplotypes can aid in understanding malaria transmission dynamics.
Universal applicability of microhaplotypes requires further validation.