Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oogenesis02:07

Oogenesis

63.5K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
63.5K
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

5
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
5
Menopause01:28

Menopause

143
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
143
Meiosis vs. Mitosis02:57

Meiosis vs. Mitosis

53.1K
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
53.1K
Infertility in Females01:28

Infertility in Females

288
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
288
Teratogenicity01:07

Teratogenicity

2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Cardiology : new 2025 guidelines].

Revue medicale suisse·2026
Same author

[Regenerative and functional gynecology in 2025 Promises, evidence, and current clinical applications].

Revue medicale suisse·2026
Same author

Breastfeeding with HIV in a high-income setting: equipoise and beyond - time to question the zero-risk policy.

Swiss medical weekly·2026
Same author

Influence of women's legal status on pregnancy outcomes and quality of care: Findings from the Pregnancy of Migrants in Switzerland (PROMISES) program.

PLOS global public health·2025
Same author

[Gynecology-obstetrics. Contribution of maternal haemodynamics during pregnancy].

Revue medicale suisse·2025
Same author

Impact of hormonal therapy on HIV-1 immune markers in cis women and gender minorities.

HIV medicine·2024

Related Experiment Video

Updated: Jun 10, 2025

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
06:11

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

Published on: May 17, 2024

511

[Pregnancies at advanced maternal age].

Océane Pécheux1, Luca Pesenti1, Begoña Martinez De Tejada1

  • 1Service d'obstétrique, Département de la femme, l'enfant et l'adolescent, Hôpitaux universitaires de Genève, 1211 Genève 14.

Revue Medicale Suisse
|October 21, 2024
PubMed
Summary

Advanced maternal age (AMA), typically defined as 40 years, increases risks for both mothers and babies. This includes higher rates of comorbidities, pregnancy complications, and adverse fetal outcomes, necessitating careful perinatal care.

More Related Videos

Human Egg Maturity Assessment and Its Clinical Application
08:51

Human Egg Maturity Assessment and Its Clinical Application

Published on: August 19, 2019

19.1K
Fertility Preservation in Patients with Severe Ovarian Dysfunction
12:03

Fertility Preservation in Patients with Severe Ovarian Dysfunction

Published on: March 25, 2021

4.5K

Related Experiment Videos

Last Updated: Jun 10, 2025

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
06:11

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

Published on: May 17, 2024

511
Human Egg Maturity Assessment and Its Clinical Application
08:51

Human Egg Maturity Assessment and Its Clinical Application

Published on: August 19, 2019

19.1K
Fertility Preservation in Patients with Severe Ovarian Dysfunction
12:03

Fertility Preservation in Patients with Severe Ovarian Dysfunction

Published on: March 25, 2021

4.5K

Area of Science:

  • Obstetrics and Gynecology
  • Perinatal Medicine
  • Reproductive Health

Context:

  • The definition of advanced maternal age (AMA) is debated, with risks increasing from age 35, but a threshold of 40 years is internationally adopted.
  • Patients with AMA often present with more comorbidities like type 2 diabetes and chronic arterial hypertension.
  • International guidelines use age 40 as a threshold for adjusting surveillance and delivery timing between 39-40 weeks.

Purpose:

  • To summarize the maternal and fetal risks associated with advanced maternal age.
  • To highlight the importance of considering AMA as a non-modifiable risk factor in perinatal care.
  • To underscore the need for tailored surveillance and management strategies for pregnancies in women aged 40 and above.

Summary:

  • Advanced maternal age (AMA) is associated with a higher incidence of maternal comorbidities including type 2 diabetes and chronic hypertension.
  • Pregnancy complications in AMA include increased risk of miscarriage, gestational diabetes, hypertensive disorders, thrombotic events, and psychiatric issues.
  • Fetal and neonatal complications linked to AMA encompass genetic anomalies, fetal growth restriction, stillbirth, prematurity, and higher rates of cesarean delivery, placenta previa, and placental abruption.

Impact:

  • Recognizing AMA as a significant risk factor is crucial for optimizing perinatal outcomes.
  • Tailored obstetric management and increased surveillance are essential for mitigating risks in pregnancies with AMA.
  • This information supports evidence-based clinical practice for improved maternal and infant health outcomes in older mothers.