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Updated: Jun 10, 2025
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Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
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Characteristics and Outcomes of Patients With Valvular Cardiogenic Shock
Raunak M Nair1, Sanchit Chawla2, Feras Alkhalaileh3
1Cleveland Clinic Heart, Vascular and Thoracic Institute, Cleveland, OH, USA.
JACC. Advances
|October 21, 2024
Summary
Valvular cardiogenic shock (VCS) affects older females and has worse outcomes than other CS forms. Surgical intervention offers the best results for VCS patients.
Area of Science:
- Cardiology
- Critical Care Medicine
- Cardiac Surgery
Background:
- Clinical characteristics and outcomes of cardiogenic shock (CS) secondary to primary valvular dysfunction (valvular CS or VCS) are not well understood.
- VCS represents a significant subset of CS cases, necessitating further investigation into its unique features and patient trajectories.
Purpose of the Study:
- To characterize the cohort of patients experiencing VCS.
- To compare the outcomes of VCS patients with those suffering from other forms of CS.
Main Methods:
- Retrospective analysis of 2,754 CS patients admitted to a cardiac intensive care unit from 2010 to 2021.
- Comparison of clinical characteristics and outcomes between patients with and without VCS.
Main Results:
- VCS accounted for 16% (442 patients) of CS admissions.
- VCS patients were older, more frequently female, and predominantly had native aortic valve dysfunction.
- VCS was associated with significantly higher 30-day and 1-year all-cause mortality compared to non-VCS.
Conclusions:
- VCS is linked to adverse short- and long-term outcomes.
- Native valve dysfunction, particularly of the aortic valve, is the primary driver of VCS.
- Surgical intervention is associated with superior outcomes in VCS, highlighting the need for timely and definitive treatment strategies.
Keywords:
cardiac critical carecardiogenic shockpercutaneous treatmentvalve replacement or repairvalvular cardiogenic shockMore Related Videos
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