Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Renewal of Intestinal Stem Cells01:23

Renewal of Intestinal Stem Cells

2.5K
The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the...
2.5K
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

125
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
125
Large Intestine01:09

Large Intestine

553
The large intestine is divided into three main regions: the cecum, colon, and rectum. Extending from the ileocecal valve to the anus, it frames the small intestine on three sides.
The ileocecal sphincter, a mucous membrane fold, guards the opening from the ileum to the large intestine. This valve permits material from the small intestine to pass into the large intestine. Attached to the ileocecal valve is the cecum. This small pouch, approximately 6 cm long, has a twisted, coiled tube known as...
553
Role Of Notch Signalling In Intestinal Stem Cell Renewal01:12

Role Of Notch Signalling In Intestinal Stem Cell Renewal

2.1K
Notch signaling was first discovered in Drosophila melanogaster, where it is involved in cell lineage differentiation. Notch signaling regulates the maintenance and differentiation of intestinal stem cells or ISCs by controlling the expression of atonal homolog 1 or Atoh1. Atoh1 directs cells to differentiate into secretory cells.
Direct cell-to-cell contact is needed for the activation of Notch signaling. The signal is initiated when a notch ligand binds to a receptor on an adjacent cell, also...
2.1K
Histology of the Small Intestine01:27

Histology of the Small Intestine

546
The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
546
Anatomy of the Intestines01:23

Anatomy of the Intestines

71.4K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Graph-augmented transformer ensemble framework for robust and scalable fake news detection in social media ecosystems.

Scientific reports·2025
Same author

Unveiling the response of efflux pump genes to delamanid in Mycobacterium tuberculosis H37Rv: a transcriptomic analysis.

Gene·2025
Same author

Monochorionic-Monoamniotic Twins Discordant for Anencephaly: Story of Expectant Management.

Journal of obstetrics and gynaecology of India·2025
Same author

A multi-omics microbiome signature is associated with the benefits of gastric bypass surgery and is differentiated from diet induced weight loss through 2 years of follow-up.

Mucosal immunology·2025
Same author

Author Correction: Integration of whole-body [<sup>18</sup>F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes.

Scientific reports·2024
Same author

Late Onset Vitamin K Deficiency Bleeding in a Neonate and Role of Elevated PIVKA-II Levels.

Indian journal of pediatrics·2024

Related Experiment Video

Updated: Jun 10, 2025

Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

14.9K

Intestinal Atresia Leading to Intussusception: An Unconventional Submission.

Mohammad Shahbaz Alam1, Salah Eidin Elghote2, Sherif Mohamed Mosad Kamel3

  • 1Neonatology, Zulekha Hospital, Dubai, ARE.

Cureus
|October 21, 2024
PubMed
Summary
This summary is machine-generated.

This case report details a newborn with ileal atresia caused by a late-pregnancy vascular accident, leading to ileocolic intussusception. It highlights how type 3A intestinal atresia can cause telescoping, emphasizing prompt surgical intervention for survival.

Keywords:
congenital ileal atresiaintestinal atresiaintrauterine intussusceptionintussusceptionjejunoileal atresia

More Related Videos

A Mouse Model of Intestinal Partial Obstruction
07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

21.1K
Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

540

Related Experiment Videos

Last Updated: Jun 10, 2025

Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

14.9K
A Mouse Model of Intestinal Partial Obstruction
07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

21.1K
Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

540

Area of Science:

  • Pediatric Surgery
  • Neonatal Medicine
  • Gastrointestinal Pathophysiology

Background:

  • Intestinal atresia is commonly attributed to intrauterine vascular accidents.
  • Intussusception is frequently cited as the primary underlying mechanism.

Observation:

  • A case of a full-term newborn with ileal atresia secondary to a late-pregnancy vascular event is presented.
  • This event led to ileocolic intussusception, a specific presentation of the condition.

Findings:

  • The case supports the understanding that type 3A intestinal atresia can result in distal segment telescoping, causing intussusception.
  • This specific pathophysiology offers a new perspective on the condition's development.

Implications:

  • Early recognition and emergency laparotomy are critical for favorable outcomes in neonates with intestinal atresia and intussusception.
  • Expert surgical management is paramount for the survival and recovery of affected infants.