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Related Experiment Video

Updated: Jun 10, 2025

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Differentiating Multisystem Inflammatory Syndrome From Neonatal Sepsis: A Case Report.

Aditi Rawat¹, Sagar Karotkar², Mahaveer S Lakra²

¹Neonatology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

|October 21, 2024

Summary

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause severe multisystem inflammatory syndrome (MIS) in neonates. Transplacental transfer of maternal antibodies and cytokines may contribute to this severe infant immune response.

Area of Science:

Neonatal immunology
Pediatric infectious diseases
Viral pathogenesis

Background:

Keywords:

mis-c mis-n multisystem inflammatory syndrome neonatal sepsis sars-cov-2

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Last Updated: Jun 10, 2025

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Published on: June 24, 2020

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a wide range of clinical outcomes.
Young infants are at higher risk for severe disease.
The exact cause of multisystem inflammatory syndrome (MIS) in SARS-CoV-2-infected neonates is not fully understood, but immune dysregulation post-infection is suspected.