Related Experiment Video
Updated: Jun 10, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
Depression Rates in Youth With Type 1 Diabetes During the COVID-19 Pandemic: Data From the T1D Exchange Quality
Alissa Roberts1, Sarah Corathers2, Robert Rapaport3
1University of Washington, Department of Pediatrics, Seattle, WA.
Depression rates in youth with type 1 diabetes remained stable during the COVID-19 pandemic. Factors like female sex, public insurance, and higher A1C were linked to increased depressive symptoms in adolescents with diabetes.
Area of Science:
- Endocrinology
- Psychiatry
- Public Health
Background:
- Type 1 diabetes (T1D) management requires continuous self-care, posing potential mental health challenges.
- The COVID-19 pandemic introduced unprecedented stressors, potentially impacting the mental well-being of adolescents with chronic conditions.
- Understanding depression prevalence and risk factors in youth with T1D during the pandemic is crucial for targeted support.
Purpose of the Study:
- To compare the rates of moderate-to-severe depressive symptoms in youth with T1D before and during the COVID-19 pandemic.
- To identify demographic and clinical characteristics associated with moderate-to-severe depressive symptoms among these youth during the pandemic.
Main Methods:
- Utilized data from the T1D Exchange Quality Improvement Collaborative.
- Compared depression screening rates pre-pandemic versus during the COVID-19 pandemic.
- Analyzed characteristics of youth screening positive for depression during the pandemic.
Main Results:
- Rates of moderate-to-severe depressive symptoms remained stable, ranging from 9.6% to 10.7% before and during the pandemic.
- During the pandemic, youth screening positive for depression were more likely to be female, have public insurance, higher A1C levels, and a history of diabetic ketoacidosis or severe hypoglycemia.
- Youth screening positive for depression were less likely to identify as non-Hispanic White and more likely to identify as Hispanic.
Conclusions:
- The COVID-19 pandemic did not significantly alter the overall prevalence of moderate-to-severe depressive symptoms in youth with T1D.
- Specific subgroups, including females, those with public insurance, higher glycemic burden (A1C), and a history of diabetes complications, faced higher risks.
- The findings highlight the importance of tailored mental health screening and support for vulnerable populations of adolescents with T1D, particularly during public health crises.
Related Concept Videos
Depressive Disorders: MDD and Dysthymia
Long-term Depression
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Depression: Overview
Diabetes Mellitus: Type 2 and Gestational
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

