Reach and effectiveness of a HEARTS hypertension pilot project in Guatemala
Irmgardt Alicia Wellmann1, José Javier Rodríguez1, Benilda Batzin2
1Institute of Nutrition of Central America and Panama Research Center for Prevention of Chronic Diseases Institute of Nutrition of Central America and Panama Guatemala City Guatemala Institute of Nutrition of Central America and Panama, Research Center for Prevention of Chronic Diseases, Institute of Nutrition of Central America and Panama, Guatemala City, Guatemala.
Insights
The World Health Organization
Area of Science:
- Cardiovascular disease research
- Public health interventions
- Hypertension management
Background:
- The World Health Organization Global Hearts initiative (HEARTS) provides a technical package to improve population-level management of hypertension and cardiovascular disease risk factors.
- Primary health care systems are crucial for managing chronic conditions like hypertension, especially in resource-limited settings.
- Implementing standardized, evidence-based protocols is essential for effective hypertension control.
Purpose of the Study:
- To describe the first pilot implementation of the HEARTS technical package within Guatemala's Ministry of Health (MOH) primary health care system.
- To evaluate the feasibility and outcomes of adapting HEARTS strategies for sustainability in rural indigenous communities.
- To assess the impact of the HEARTS intervention on patient reach and blood pressure control using the RE-AIM framework.
Main Methods:
- A pilot project was conducted in six primary health care facilities across three rural indigenous municipalities in Guatemala, starting April 2022.
- HEARTS-aligned strategies were adapted for local sustainability.
- Outcomes were measured using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework, focusing on treatment count and blood pressure control metrics.
Main Results:
- A statistically significant increase in monthly hypertension treatment counts was observed post-implementation (25 patients/month increase, P=.002, followed by 2.4 additional patients/month, P=.005).
- Mean systolic blood pressure decreased significantly (-4.4 mmHg, P=0.028), while diastolic blood pressure showed a non-significant trend towards reduction (-0.9 mmHg, P=0.376).
- The proportion of patients achieving blood pressure control (<130/80 mmHg) increased from 33.4% at baseline to 47.1% at 6 months (adjusted change 13.7%, P=0.027).
Conclusions:
- The HEARTS model is feasible for implementation within the Guatemalan Ministry of Health's primary health care system.
- The intervention demonstrated positive impacts on patient reach and blood pressure control, particularly in rural, indigenous populations.
- Findings support the scalability of the HEARTS program for improving hypertension management nationwide, reaching the majority of patients seeking care.
Abstract:
The World Health Organization Global Hearts initiative (HEARTS) and technical package aim to improve the primary health care management of hypertension and other risk factors for cardiovascular disease at the population level. This study describes the first HEARTS implementation pilot project in Guatemala's Ministry of Health (MOH) primary health care system. This pilot began in April 2022 in six primary health care facilities in three rural indigenous municipalities. The project consisted of HEARTS-aligned strategies adapted to enhance program sustainability in Guatemala. Outcomes were defined using the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) framework. The primary reach outcome was treatment count, defined as the absolute number of patients per month receiving medication treatment for hypertension. The primary effectiveness outcomes were mean systolic blood pressure (BP), mean diastolic BP, and proportion of patients with BP control (<130/80 mmHg). In the first month of the post-implementation period, there was a statistically significant increase of 25 patients treated per month above the baseline of 20 to 25 patients (P = .002), followed by a significant increase of 2.4 additional patients treated each month (P = .005) thereafter. The mean change in systolic BP was -4.4 (95% CI, -8.2 to -0.5; P = 0.028) mmHg, and the mean change in diastolic BP was -0.9 (95% CI, -2.8 to 1.1; P = .376) mmHg. The proportion of the cohort with BP control increased from 33.4% at baseline to 47.1% at 6 months (adjusted change, 13.7%; 95% CI, 2.2% to 25.2%; P = .027). These findings support the feasibility of implementing the HEARTS model for BP control throughout the MOH primary health care system, which is where most Guatemalans with hypertension seek care.
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