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Published on: May 14, 2013
Anticoagulant-Related Nephropathy as a Cause of Early Graft Dysfunction
Pilar Musalem1, Juan Pablo Silva-Carvajal, Hans Müller-Ortiz
1>From the Nephrology, Dialysis and Transplantation Service, Las Higueras Hospital, Talcahuano, Chile; and the Departamento de Medicina Interna, Facultad de Medicina, Universidad de Concepción, Concepción, Chile.
Abstract:
Anticoagulant-related nephropathy is an increasingly recognized entity, characterized by the presence of hematuria in the context of a supratherapeutic international normalized ratio with the development of secondary acute kidney injury, which may require renal replacement therapy and may progress to chronic kidney disease. We present the case of a 63-year-old patient who started anticoagulant therapy with acenocoumarol 2 months after her kidney transplant and presented with graft dysfunction concomitant to a supratherapeutic international normalized ratio.
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