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Transcatheter vacuum-assisted aspiration of large intracardiac and intravascular masses

Laura Besola, Alessandro Fiocco, Nicola Nencioni

    Eurointervention : Journal of Europcr in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
    |October 21, 2024
    PubMed

    Insights

    Vacuum-assisted aspiration systems offer a minimally invasive solution for large intravascular and intracardiac masses like thrombi and vegetations. This review details clinical outcomes of using these systems for diverse mass removals.

    Area of Science:

    • Cardiovascular Medicine
    • Interventional Cardiology
    • Medical Device Technology

    Background:

    • Intravascular and intracardiac masses, including thrombi, tumors, and vegetations, affect both heart chambers and circulation.
    • Traditional treatments involve surgery or anticoagulation/fibrinolysis, often challenging for frail patients.
    • Minimally invasive alternatives are sought for complex cases, especially large masses.

    Purpose of the Study:

    • To review the clinical results of vacuum-assisted aspiration systems for treating intravascular and intracardiac masses.
    • To evaluate the efficacy and safety of the AngioVac System in diverse clinical applications.
    • To summarize the expanded use of this technology from right-sided thrombi to left-sided masses and vegetations.

    Main Methods:

    • Review of clinical outcomes associated with vacuum-assisted aspiration systems.
    • Analysis of AngioVac System applications in treating intravenous and intracardiac masses.
    • Summarization of data on efficacy for thrombi, vegetations, and tumors in both right and left heart chambers.

    Main Results:

    • Vacuum-assisted aspiration systems have been successfully applied to a range of intravascular and intracardiac masses.
    • The AngioVac System has demonstrated utility beyond initial indications, including right-sided endocarditis and left-sided thrombi/vegetations.
    • Clinical results indicate this minimally invasive approach is a viable option for complex mass removal.

    Conclusions:

    • Vacuum-assisted aspiration represents an effective, minimally invasive treatment for various intravascular and intracardiac masses.
    • The AngioVac System's versatility has expanded, offering solutions for challenging patient populations.
    • Further research into long-term outcomes and broader applications is warranted.

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