Related Experiment Video
Updated: Jun 9, 2025

02:21
Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
Published on: March 15, 2024
567
Improved Health Care Utilization Among Men With Depression Undergoing Inflatable Penile Prosthesis in a U.S.
Roei Golan1, Alysha M McGovern2, Young Eun Shin2
1Department of Urology, University of Florida College of Medicine, Gainesville, FL, USA.
American Journal of Men'S Health
|October 21, 2024
Summary
Inflatable penile prosthesis (IPP) implantation reduced depression-related healthcare visits and antidepressant use in men. This suggests IPP offers mental health benefits beyond erectile function restoration.
Area of Science:
- Urology
- Men's Health
- Mental Health
Background:
- Depression is a common comorbidity in men seeking treatment for erectile dysfunction.
- Inflatable penile prosthesis (IPP) implantation is a surgical option for severe erectile dysfunction.
Purpose of the Study:
- To evaluate depression-related healthcare resource utilization and antidepressant medication use in men who received IPP implantation.
- To determine if IPP implantation impacts mental health outcomes in men with depression.
Main Methods:
- Retrospective cohort study of commercially insured men in the US who underwent IPP implantation (2007-2020).
- Analysis of depression-related healthcare visits and antidepressant prescription data pre- and post-IPP.
- Inclusion criteria: depression diagnosis within one year prior to IPP.
Main Results:
- A significant reduction in overall depression-related healthcare visits (4.9 to 3.8) and inpatient visits (0.07 to 0.03) post-IPP.
- Significant decrease in office visits (4.25 to 3.29) and antidepressant prescriptions (7.55 to 8.09) post-IPP.
- 15% of men stopped antidepressant medication entirely post-IPP; continued users showed decreased prescriptions and refills.
Conclusions:
- IPP implantation is associated with reduced depression-related healthcare utilization and antidepressant medication use.
- IPP may provide mental health benefits for men with depression beyond improved erectile function.
- Expanded insurance coverage for IPP, particularly for men with depression, could benefit patients and insurers.
Related Concept Videos
Disorders of the Male Reproductive System
342
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
342
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
129
Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
129

