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Updated: Jun 9, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Access to 2-Oxabicyclo[2.1.1]hexanes and their use in Scaffold Hopping

Olivier Lorthioir1, Niall Anderson1, Scott Boyd1

  • 1Oncology Medicinal Chemistry, R&D AstraZeneca, The Discovery Centre (DISC), Biomedical Campus, 1 Francis Crick Ave, Trumpington, Cambridge CB2 0AA, U.K.

Organic Letters
|October 21, 2024
PubMed

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