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Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Systematisation of the causes that required revision hip replacement, methods of their solution, treatment results in
Vitalii Pidhaietskyi1, Mykhailo Pidhaietskyi2
1Department of Traumatology and Orthopedics of Adults, Institute of Traumatology and Orthopedics of the National Academy of Medical Sciences of Ukraine, Kyiv, 01601, Ukraine. vpidhaietskyi@gmail.com.
Insights
Revision hip arthroplasty (rTHA) data highlights aseptic instability as a key complication. Establishing a Ukrainian registry for hip arthroplasty (HA) is crucial for improving patient care and standardizing terminology.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
- Public Health
Background:
- Complications following total hip replacement (THA) over a decade necessitated extensive revision surgeries.
- A need exists to organize data on revision hip arthroplasty (rTHA) and standardize terminology.
Purpose of the Study:
- To analyze complications of total hip replacement (THA) requiring revision surgery over 10 years.
- To propose recommendations for an All-Ukrainian registry of hip arthroplasty (HA).
- To standardize the definition of "revision of total hip replacement surgery".
Main Methods:
- Retrospective analysis of 236 revision hip arthroplasties (rTHA) from 2005-2021.
- Identification of revision factors through medical records, lab results, and prosthesis evaluation.
- Statistical analysis using Statistica v. 12.6 (p < 0.05).
Main Results:
- Aseptic component instability was diagnosed in 41.76% of rTHA cases.
- High BMI (≥30) and older age were significant factors for mechanical loosening.
- Infectious complications were linked to chronic infectious diseases (t=3.37, p=0.001).
Conclusions:
- Standardized terminology and a comprehensive hip arthroplasty registry are urgently needed.
- Cement-free fixation is superior for aseptic instability revision; two-stage arthroplasty for infections.
- Open repositioning and osteosynthesis are effective for periprosthetic femoral fractures.
Background:
The objective of this study is to organise data on complications following total hip replacement (THA) over a span of 10 years, specifically focussing on cases that necessitated revision endoprosthetic surgeries. The objective is to create a recommendation for an All-Ukrainian registry of initial and repeated hip arthroplasty (HA) and standardise the terminology used to define "revision of total hip replacement surgery".
Methods:
The retrospective analysis examined 236 instances of revision hip arthroplasty (rTHA) performed at the Institute of Traumatology and Orthopaedics Centre between January 2005 and December 2021. The primary factors for revision were identified through an analysis of the patient's medical records, laboratory results, visual inspection, and the state of the previously implanted prosthesis. Demographic information, primary and revision HA dates, diagnoses, and causes of complications were recorded. The statistical analysis was conducted using the Statistica package (StatSoft), version 12.6 (2015), with a significance level of p < 0.05.
Results:
Out of the 364 patients who were diagnosed with complications, 236 of them (55.17%) needed a procedure called 1rTHA. Among these cases, 152 (41.76%) were specifically diagnosed with aseptic component instability. Significant factors for mechanical loosening were a high body mass index (BMI ≥ 30) and older age, with respective t-values of 2.08 (p = 0.004) and 2.59 (p = 0.045). Osteoporosis significantly contributed to aseptic loosening and fractures around the implant. The occurrence of infectious complications was frequently linked to chronic infectious diseases (t = 3.37, p = 0.001). The overall percentage of need for 2rTHA was 27.22% (43 cases), with one case of infectious lesion following the revision.
Conclusions:
The study emphasises the urgent requirement for standardised terminology and a comprehensive registry for hip arthroplasty procedures. Primary results indicate that cement-free fixation is more effective than cement-based fixation for revision in patients with aseptic instability and that two-stage arthroplasty is effective for treating infectious inflammation. Furthermore, the most effective treatment for femoral fractures with periprosthetic involvement was determined to be open repositioning and osteosynthesis with metal retainers. The aforementioned observations emphasise the need to create a comprehensive registry across Ukraine to support patient care, enable evidence-based practices, and enhance the overall effectiveness of hip arthroplasty operations.
Clinical Trial Number:
Not applicable.
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