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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
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Immediate Prepectoral Breast Reconstruction Without Acellular Dermal Matrices: Preliminary Results
Gabriel Bouhadana1, Yehuda Chocron2, Alain J Azzi2
1Division of Plastic Surgery, Université de Montréal, Montreal, Quebec, Canada.
Plastic Surgery (Oakville, Ont.)
|October 22, 2024
Summary
Immediate prepectoral breast reconstruction without acellular dermal matrices (ADMs) shows promising safety outcomes. This approach is particularly safe for patients with a low body mass index (BMI) and smaller implant sizes in direct-to-implant reconstructions.
Area of Science:
- Plastic Surgery
- Breast Reconstruction
- Oncologic Surgery
Background:
- Growing interest in prepectoral breast reconstruction.
- Concerns regarding the use of acellular dermal matrices (ADMs).
- Need to evaluate non-ADM-assisted techniques.
Purpose of the Study:
- To assess the safety and complications of immediate prepectoral breast reconstruction without ADM.
- To identify patient and implant factors associated with adverse outcomes.
Main Methods:
- Retrospective cohort study of 66 patients (88 breasts) undergoing prepectoral reconstruction without ADM.
- Data collected on demographics, oncologic management, and surgical outcomes.
- Follow-up averaged 7.8 months.
Main Results:
- Overall implant failure rate was 5.7%.
- Major complications included periprosthetic infections (5.7%) and nipple-areolar necrosis (2%).
- Increased implant size and BMI were linked to higher complication rates in direct-to-implant (DTI) cases.
Conclusions:
- Immediate prepectoral breast reconstruction without ADM appears to be a safe option.
- The technique is particularly safe for patients with low BMI and implants <500cc in DTI reconstruction.
- Further large prospective studies are needed to validate these findings.

