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Related Experiment Video

Updated: Jun 9, 2025

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Maxillectomy and its ophthalmic implications: A comprehensive analysis over 20 years.

Tae Eun Kee1, Chan Woong Joo1, Won Sup Lee2

  • 1Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, South Korea.

Heliyon
|October 22, 2024
PubMed
Summary

Maxillectomy surgery frequently causes ophthalmic complications, with 95.6% of patients experiencing issues like cornea and eyelid problems. Orbital floor resection and radiotherapy are significant risk factors for these vision-impacting complications.

Keywords:
MaxillectomyMultidisciplinary approachOphthalmic complications

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Area of Science:

  • Ophthalmology
  • Head and Neck Surgery
  • Oncology

Background:

  • Maxillectomy is a crucial surgery for head and neck cancers.
  • This procedure can significantly impact orbital structures, leading to various ophthalmic complications.

Purpose of the Study:

  • To evaluate the extent and severity of ophthalmic complications following maxillectomy.
  • To identify risk factors associated with these complications.

Main Methods:

  • A 20-year retrospective observational cohort study of 101 patients who underwent maxillectomy.
  • Analysis of medical records for demographics, surgical details, and ophthalmic complications.
  • Statistical analysis, including multivariate analysis, to identify risk factors.

Main Results:

  • 95.6% of patients experienced at least one ophthalmic complication, most commonly affecting the cornea/conjunctiva (56%), eyelid (48.4%), and lacrimal system (38.5%).
  • Orbital floor resection and radiotherapy were identified as significant risk factors for specific complications.
  • Many patients experienced multiple complications, requiring secondary ophthalmic surgeries such as dacryocystorhinostomy and tarsorrhaphy.

Conclusions:

  • Maxillectomy patients face a high incidence of ophthalmic complications.
  • Surgical extent and adjuvant therapies like radiotherapy are key influencing factors.
  • A multidisciplinary approach is vital for managing these complications and improving patient quality of life.