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[Lower motor neuron disease with MRI «snake eyes» pattern].
L V Brylev1, V V Bryukhov2, E S Druzhinina3
1Solovev Moscow Research and Clinical Center for Neuropsychiatry, Moscow, Russia.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|October 22, 2024
Summary
This study details a rare case of motor neuron disease affecting the lower motor neuron in the cervical spine. The distinctive "snake eyes" MRI finding in the pyramidal tract influenced diagnosis and prognosis.
Area of Science:
- Neurology
- Neuroscience
- Radiology
Background:
- Motor neuron disease (MND) typically involves widespread neurological damage.
- Isolated lower motor neuron lesions at a single pyramidal tract level are diagnostically rare.
- Asymmetric cervical lesions present unique clinical and imaging challenges.
Purpose of the Study:
- To analyze a rare case of asymmetric lower motor neuron lesion at the cervical level.
- To correlate clinical findings with advanced imaging.
- To evaluate the diagnostic and prognostic significance of the "snake eyes" MRI sign.
Main Methods:
- Case study analysis.
- Clinical examination and manifestation review.
- Magnetic Resonance Imaging (MRI) of the cervical spine.
- Longitudinal patient observation.
Main Results:
- The patient presented with asymmetric lower motor neuron signs.
- MRI revealed characteristic "snake eyes" changes in the cervical pyramidal tracts.
- These imaging findings were crucial for diagnosis and predicting disease course.
Conclusions:
- The "snake eyes" sign is a key indicator in diagnosing rare MND presentations.
- Understanding this MRI finding improves diagnostic accuracy and prognostic assessment in specific lower motor neuron diseases.
- This case highlights the importance of detailed imaging in neurological diagnostics.

