Related Experiment Video
Updated: Jun 21, 2026

Preparation of Viral DNA from Nucleocapsids
Published on: August 16, 2011
Logistics for Rapid Isolation of Viruses From Humans
Philip Bacchus1, Wanda Christ1, Arian Frisell1
1Philip Bacchus is a Commander, Alexander Potapeiko and Anna-Clara Markström are Privates First Class, and Felicia Leopoldson is a Corporal; all at the National CBRN Defence Centre, Swedish Armed Forces, Umeå, Sweden. Philip Bacchus is also a PhD Student, and David Gisselsson, MD, PhD, is a Senior Consultant and Professor; both in the Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden. Arian Frisell is a Biomedical Scientist; Ulrika Marking, MD, MPH, is an Infectious Disease Analyst; Andreas Bråve, PhD, is Deputy Head; Kim Blom, PhD, is a Project Manager and Immunologist; and Ramona Groenheit, PhD, is a Microbiologist; all in the Department of Microbiology, Public Health Agency of Sweden, Solna, Sweden. Ulrika Marking is also a PhD Student; Nina Greilert-Norin, RN, is a Research Nurse; Sebastian Havervall, MD, is Consultant and a PhD Student; and Charlotte Thålin, MD, PhD, is Affiliated to Research/Docent; all in the Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden. Wanda Christ, MSc, PhD, is a Postdoctoral Researcher, Department of Micorbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden. Jonas Klingström, PhD, is a Professor, Division of Molecular Medicine and Virology, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Abstract:
An important aspect of microbiological surveillance is the ability to access live viruses for microneutralization assays, which enables the study of viral characteristics and mechanisms in vitro and production of positive controls for diagnostic methods. During the COVID-19 pandemic, the Public Health Agency of Sweden established a protocol for the rapid collection of clinical samples and subsequent isolation of novel virus variants.
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