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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Emergency department management of acute pediatric sickle cell disease complications

Kathleen M Jackson1, Bradley Beamon2, Erika B Crawford3

  • 1Clinical Assistant Professor, Graduate Medical Education; Assistant Director of Pediatrics, Emergency Medicine Residency Program, Department of Emergency Medicine, Division of Pediatric Emergency Medicine, University of South Carolina School of Medicine, Prisma Health Upstate, Greenville, SC.

Pediatric Emergency Medicine Practice
|October 22, 2024
PubMed

Insights

Pediatric sickle cell disease (SCD) complications frequently require emergency care. This review details acute SCD issues and evidence-based emergency management for children.

Area of Science:

  • Pediatric Emergency Medicine
  • Hematology
  • Clinical Review

Background:

  • Sickle cell disease (SCD) presents common chronic conditions in pediatric emergency departments.
  • Effective management requires emergency clinicians to understand SCD features, complications, and treatments.
  • Evidence-based care is crucial for pediatric patients with SCD.

Purpose of the Study:

  • To review the acute complications of sickle cell disease in pediatric patients.
  • To outline evidence-based emergent management strategies for pediatric SCD.

Main Methods:

  • Literature review of acute complications in pediatric sickle cell disease.
  • Synthesis of current evidence for emergency management protocols.

Main Results:

  • Common acute complications of pediatric SCD include vaso-occlusive events, acute chest syndrome, and infections.
  • Early recognition and prompt intervention are critical for managing SCD complications.
  • Treatment modalities focus on pain management, hydration, oxygenation, and infection control.

Conclusions:

  • Emergency clinicians must be proficient in diagnosing and managing acute SCD complications in children.
  • Adherence to evidence-based guidelines improves outcomes for pediatric patients with SCD emergencies.
  • This review provides a framework for high-quality emergent care of pediatric SCD.

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