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Updated: Jul 27, 2026

Monitoring Tumor Metastases and Osteolytic Lesions with Bioluminescence and Micro CT Imaging
Published on: April 14, 2011
MFP-YOLO: a multi-scale feature perception network for CT bone metastasis detection
Wenrui Lu1, Wei Zhang2, Yanyan Liu3
1School of Microelectronics, Tianjin University, 300072, Tianjin, China.
Abstract:
Bone metastasis is one of the most common forms of metastasis in the late stages of malignancy. The early detection of bone metastases can help clinicians develop appropriate treatment plans. CT images are essential for diagnosing and assessing bone metastases in clinical practice. However, early bone metastasis lesions occupy a small part of the image and display variable sizes as the condition progresses, which adds complexity to the detection. To improve diagnostic efficiency, this paper proposes a novel algorithm-MFP-YOLO. Building on the YOLOv5 algorithm, this approach introduces a feature extraction module capable of capturing global information and designs a new content-aware feature pyramid structure to improve the network's capability in processing lesions of varying sizes. Moreover, this paper innovatively applies a transformer-structure decoder to bone metastasis detection. A dataset comprising 3921 CT images was created specifically for this task. The proposed method outperforms the baseline model with a 5.5% increase in precision and a 7.7% boost in recall. The experimental results indicate that this method can meet the needs of bone metastasis detection tasks in real scenarios and provide assistance for medical diagnosis.

