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Updated: Jun 9, 2025

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
Published on: August 9, 2019
Pioneering role of RNA in the early evolution of life
Israel Muñoz-Velasco1, Adrián Cruz-González2, Ricardo Hernández-Morales2
1Universidad Nacional Autónoma de México, Facultad de Ciencias, Departamento de Biología Celular, Mexico City, Mexico.
Abstract:
The catalytic, regulatory and structural properties of RNA, combined with their extraordinary ubiquity in cellular processes, are consistent with the proposal that this molecule played a much more conspicuous role in heredity and metabolism during the early stages of biological evolution. This review explores the pivotal role of RNA in the earliest life forms and its relevance in modern biological systems. It examines current models that study the early evolution of life, providing insights into the primordial RNA world and its legacy in contemporary biology.
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