Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Discovery: Overview01:26

Drug Discovery: Overview

Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
Structure-Activity Relationships and Drug Design01:28

Structure-Activity Relationships and Drug Design

Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence its...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Metal Hydrogen-Bonded Organic Framework Constructed by an Aggregation-Caused-Quenching Fluorophore, but Achieving "Turn-On" Sensing Capacity.

Inorganic chemistry·2026
Same author

Erratum: Mining resistance genes of soybean cyst nematode based on genome-wide association study.

Frontiers in plant science·2026
Same author

DDIT3, OTUB2, and ASS1 regulate arginine biosynthesis in colorectal cancer cells under arginine deficiency.

Cell reports·2026
Same author

Probing Scalar-Neutrino and Scalar-Dark-Matter Interactions with PandaX-4T.

Physical review letters·2026
Same author

Balancing cancer and comorbidity: a multicenter qualitative study on how comorbidity shapes survivorship care preferences in China.

Journal of cancer survivorship : research and practice·2026
Same author

Ultrasound in Pulmonary Embolism: A Bibliometric Analysis of Trends and Hotspots (1978-2025).

Seminars in ultrasound, CT, and MR·2026

Related Experiment Video

Updated: Jun 12, 2026

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

17.3K

Hydrogel Strategies for Female Reproduction Dysfunction.

Minxuan Jia1,2,3, Jiamin Wang4,5,6, Chubing Lin1,2,3

  • 1New Cornerstone Science Laboratory, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, China.

ACS Nano
|October 22, 2024
PubMed
Summary

Hydrogels show promise for treating female infertility by reconstructing reproductive organs. This approach offers new therapeutic avenues for ovarian, uterine, and fallopian tube dysfunction.

Keywords:
bioactive biomaterialsbiomimetic ovarian follicle structureendometrial receptivityendometriumfallopian tubesfemale infertilityfertility restorationhydrogelovariesuterus

More Related Videos

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
09:30

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications

Published on: October 7, 2016

11.2K
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

7.7K

Related Experiment Videos

Last Updated: Jun 12, 2026

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

17.3K
The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
09:30

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications

Published on: October 7, 2016

11.2K
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

7.7K

Area of Science:

  • Reproductive Biology
  • Biomaterials Science
  • Regenerative Medicine

Background:

  • Female infertility affects over 50% of infertility cases, often stemming from reproductive system dysfunction.
  • Current treatments include medications, surgery, and assisted reproductive technologies, with limitations in efficacy and translation from animal models.
  • The female reproductive system's complexity presents challenges for effective infertility treatment.

Purpose of the Study:

  • To review the physiology and pathology of the female reproductive system in relation to infertility.
  • To discuss the limitations of existing infertility treatments and the gap in animal model translation.
  • To explore the potential of hydrogels in treating female reproductive system dysfunction.

Main Methods:

  • Literature review of hydrogel applications in female reproductive reconstruction.
  • Analysis of current infertility treatment modalities and their shortcomings.
  • Examination of hydrogel properties relevant to tissue engineering and organ reconstruction.

Main Results:

  • Hydrogels offer biocompatibility, low immunogenicity, and tunable properties for organ reconstruction.
  • Hydrogel-based strategies can target pathological mechanisms of ovarian, endometrial/uterine, and fallopian tube dysfunction.
  • Significant challenges remain in translating hydrogel therapies from preclinical studies to human applications.

Conclusions:

  • Hydrogels represent a promising biomaterial for developing novel treatments for female infertility.
  • Hydrogel-based strategies hold potential for advancing translational medicine in reproductive health.
  • Further research is needed to overcome challenges and realize the full clinical potential of hydrogels for female reproductive reconstruction.