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Related Concept Videos

Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

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Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
211
Acute Pharyngitis01:30

Acute Pharyngitis

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Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
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Sputum Studies II: Culture and Sensitivity01:20

Sputum Studies II: Culture and Sensitivity

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Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
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Tonsillitis II: Management01:26

Tonsillitis II: Management

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This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
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Chronic Pharyngitis01:23

Chronic Pharyngitis

1.3K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
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Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

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Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
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Related Experiment Video

Updated: Jun 9, 2025

Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae
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Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae

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Extensive Invasive Sinusitis Secondary to Streptococcus Intermedius Infection.

McKenna Morrow1, Mari Ogino2, Alay Shah3

  • 1School of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA mmorrow@mcw.edu.

Clinical Medicine & Research
|October 22, 2024
PubMed
Summary

A rare invasive sinusitis case in a 72-year-old woman, caused by Streptococcus intermedius, was successfully treated with antibiotics alone. This highlights potential medical management for invasive sinusitis when surgery is contraindicated.

Keywords:
Bacterial sinusitisCavernous sinus thrombosisInvasive sinusitisOrbital cellulitis

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Otolaryngology

Background:

  • Invasive sinusitis is a rare but serious complication of sinusitis.
  • Streptococcus intermedius is an uncommon pathogen in acute bacterial sinusitis, often linked to severe infections and intracranial complications.

Observation:

  • A 72-year-old woman presented with acute encephalopathy and sepsis.
  • Imaging revealed extensive invasive sinusitis with intracranial extension.

Findings:

  • The patient was diagnosed with invasive sinusitis caused by Streptococcus intermedius.
  • She was successfully treated with intravenous antibiotics alone, without surgical intervention.

Implications:

  • This case suggests that medical management alone may be a viable option for invasive sinusitis, particularly when surgery is contraindicated.
  • Further investigation into factors enabling successful medical management alone is warranted to improve patient outcomes and reduce morbidity/mortality associated with this condition.