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Addressing Inpatient Hyponatremia Through Targeted Automatic E-consults: A Pilot Randomized Trial
Timothy J Judson1, Lowell Lo2, John E Demko2
1Department of Medicine, University of California San Francisco, San Francisco, CA, USA. Timothy.judson@ucsf.edu.
Targeted automatic electronic consultations (TACos) for hyponatremia were feasible and acceptable, often changing patient management. Further research is needed to confirm their impact on clinical outcomes and cost-effectiveness.
Area of Science:
- Nephrology
- Internal Medicine
- Health Informatics
Background:
- Hyponatremia is a common hospital-acquired electrolyte disorder with suboptimal correction rates.
- Limited nephrologist resources hinder timely diagnosis and treatment of hyponatremia.
- Targeted automatic electronic consultations (TACos) offer a scalable model for expert nephrology guidance.
Purpose of the Study:
- To assess the feasibility and acceptability of a TACo intervention for hospitalized patients with hyponatremia.
- To evaluate the impact of TACos on hyponatremia diagnosis and management.
Main Methods:
- A single-site, parallel-group cluster randomized trial was conducted.
- Adult inpatients with hyponatremia were enrolled.
- Nephrologists provided daily TACos with diagnostic and therapeutic recommendations.
Main Results:
- 68% of intervention patients benefited from TACos, with a mean of 2.6 e-consults per patient.
- 78% of physicians reported TACos changed their management, and 83% desired continuation.
- Clinical outcomes, including hyponatremia resolution, length of stay, readmissions, and costs, were similar between groups.
Conclusions:
- Inpatient TACos for hyponatremia are feasible and acceptable to clinical teams.
- TACos frequently influenced hyponatremia diagnosis and management strategies.
- Further investigation is required to establish the clinical and cost-effectiveness of the TACo model.
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