Invasive Pulmonary Infection of Malassezia Species in a Patient With Ulcerative Colitis: A Case Report
Aya Yamada1, Yuko Nishimoto2, Ryosuke Taiji1
1Department of Diagnostic and Interventional Radiology.
Abstract:
Malassezia species are lipophilic yeasts recognized for causing skin manifestations, such as pityriasis versicolor. In addition, Malassezia can lead to invasive infection, mostly intravascular catheter-associated sepsis-related lipid-containing total parenteral nutrition in neonates and immunocompromised hosts. We experienced a case of invasive pulmonary Malassezia infection in a patient with refractory ulcerative colitis undergoing immunosuppressive treatment without lipid-containing total parenteral nutrition. Computed tomography (CT) images showed multiple lung nodules with CT halo signs. Finally, he underwent a partial right middle lobectomy and was diagnosed with invasive pulmonary malasseziosis through a genetic analysis. Multiple lung nodules on CT images may be found in invasive pulmonary malasseziosis in immunosuppressed patients with a central venous catheter.
Insights
Invasive pulmonary malasseziosis, a rare fungal infection, can occur in immunocompromised patients. This case highlights multiple lung nodules with CT halo signs as a potential indicator in such individuals.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Pulmonology
Background:
- Malassezia species are lipophilic yeasts commonly associated with superficial skin conditions like pityriasis versicolor.
- Invasive Malassezia infections, often linked to central venous catheters and lipid-containing parenteral nutrition, primarily affect neonates and immunocompromised individuals.
- Pulmonary involvement by Malassezia is rare, with limited reported cases, particularly in patients not receiving lipid-based parenteral nutrition.
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